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All functions

DosingData
Dosing data class (R6 class)
JointData
Joint data class (R6 class)
MultistateModel
Main model class
MultistateModelFit
Minimal fit class
MultistateSystem
A multistate system with proportional spline hazards
PKModel
One-compartment PK Model
PSSDosingData
Partially steady-state dosing data class (R6 class)
PathData
Path data class (R6 class)
TransitionMatrix
Defines states and possible transitions
as_any_event()
PathData to time-to-event data format for any state other than null state
as_single_event()
PathData to time-to-event data format with a single event
as_survival()
PathData to event-free survival format
bmstate-package bmstate
The 'bmstate' package.
c_index()
Compute concordance index
create_msm()
Create a multistate model
create_scoring_df()
Create a data frame to evaluate state visit probability predictions
create_stan_data()
Creating Stan data list
create_stan_model()
Create the main 'Stan' model
default_stan_filepath()
Get path to default Stan file
df_to_pathdata()
Create 'PathData' from a data frame of one observed path per subject
ensure_exposed_stan_functions()
Expose 'Stan' functions if they are not yet exposed
example_sim_setup_illnessdeath()
Example simulation setup
fit_stan()
Fit a model using 'Stan'
generate_paths()
Path generation for 'MultistateModelFit'
msmfit_exposure()
Compute exposure
msmfit_inst_hazard_param_draws()
Extract and reshape draws of instant hazard related parameters
msmfit_log_hazard_multipliers()
Compute log_hazard multipliers
msmfit_pk_params()
Evaluate PK parameters
p_state_occupancy()
Solve state occupancy probabilities for each subject and draw in 'MultistateModelFit'
p_state_visit()
For each non-source state, compute probability of visiting it at least once before given time
p_state_visit_per_subject()
For each subject, compute probability of visiting a given state at least once before given time
pk_2cpt_pss()
Partially steady-state PK model
plot_stan_data_integral()
Visualize numerical integration of hazard
plot_stan_data_matrix()
Visualize parts of the 'Stan' data
plot_state_occupancy()
Plot mean state occupancy probabilities over time for each subject
potential_covariates()
Look for potential covariates that affect transitions
simulate_dosing()
Simulate dosing data
simulate_example_data()
Simulate example data
solve_time_evolution()
Solve the Kolmogorov forward equation of a Markovian multistate system
solve_trans_prob_matrix()
Solve the transition probability matrix for each given output time
split_data()
Train-test split
transmat_full() transmat_comprisk() transmat_survival() transmat_illnessdeath() transmat_progression() transmat_diamond()
Create a common transition matrix